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Kasposi's sarcoma 
Most common non-infectious AIDS-defining diagnosis in HIV disease that arises at multiple sites within short span of time. 
 
Sites
  • Skin
  • Lymph nodes
  • mouth
  • hard palate
  • tip of nose
  • penis
  • lower legs
Look of the lesion
Red, or violatous; in dark skinned people, they may appear brown or black, well-defined, flat or raised. When multiple they tend to develop along flexures.
 
Prognosis
Lymphnode involvement has poor prognosis.
 
Treatment
  • Local radiotherapy, especially for single lesions.
  • Combination chemotherapy
  • Use of anti-neoplastic drugs.
Non-hodgkin's lymphoma
Arises from: B-lymphocytes 80%, T lymphocytes.
 
Sites
  • CNS (Central Nervous System), 
  • Bone marrow, 
  • GIT (Gastro intestinal Tract), 
  • Liver.
     
Trigger factors
Fever and weight loss.
 
Treatment
Combination chemotherapy.
 
Prognosis
Poor.
Carcinoma
There is an increased incidence of cervical dysplasia and neoplasia in HIV infected females and anal carcinoma in HIV infected homosexual men. 
 

 

 

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